منابع مشابه
Nuclear RNA Turnover
In mammalian cells, significantly more RNA is turned over in the nucleus than in the cytoplasm. However, only recently have we begun to understand the mechanisms and regulation of nuclear RNA decay.
متن کاملTurnover of Hela Ribosomal Rna
A class of RNA in HeLa cytoplasm with a sedimentation value of 22S is described. This RNA is a true cytoplasmic component and is not an artifact of cell rupture or of the method of RNA preparation. The 22S RNA sediments in a sucrose gradient with those ribosomal structures containing 28S ribosomal RNA (60S and 74S particles and polyribosomes). It has a base composition and methyl content simila...
متن کاملRNA-dependent RNA polymerases, viruses, and RNA silencing.
Most viruses have RNA genomes that are replicated and transcribed into messenger RNA by viral RNA-dependent RNA polymerases (RdRps), usually in concert with other viral and host factors. Many, if not most, eukaryotes also encode putative RdRps that have been implicated in sequence-specific, RNA-triggered gene silencing. Although the viral and cellular RdRps have no sequence homology, they share...
متن کاملGlucocorticosteroids and RNA tumor viruses.
Glucocorticosteroids at physiological concentrations stimulated typeC virus production 2 to 50-fold from mouse fibroblasts induced by 5-iodo-2'deoxyuridine. They also stimulated virus production from chronically infected mouse myeloid leukemia cell line. Some potential practial applications of these findings are discussed. In 1971, D. R. Lowy, et al., reported that murine leukemia virus can be ...
متن کاملEpisodic evolution of RNA viruses.
The molecular clock and the neutral allele theory have been intimately intertwined since both were conceived in the 1960s (1-3). The molecular clock embodies the observation that rates of molecular evolution are nearly constant; the neutral allele theory provides a mechanistic explanation for the constancy. Like most relationships, that between the neutral theory and the molecular clock has had...
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ژورنال
عنوان ژورنال: RNA Biology
سال: 2006
ISSN: 1547-6286,1555-8584
DOI: 10.4161/rna.3.4.4076